1. What
is the primary purpose of immunohistochemistry in pathology?
a. Stain
nuclei
b. Visualize
antigens in tissues
c. Demonstrate
blood vessels
d. Assess
cell morphology
2. Which
enzyme is commonly used in immunohistochemistry as a chromogen?
a. Alkaline
phosphatase
b. Horseradish
peroxidase
c. β-Galactosidase
d. Glucose
oxidase
3. CD3
staining is used to identify:
a. B
cells
b. T
cells
c. Macrophages
d. Natural
killer cells
4. What
is the primary function of a secondary antibody in immunohistochemistry?
a. Bind
to antigens on tissues
b. Amplify
the signal
c. Tag
cells for phagocytosis
d. Enhance
tissue fixation
5. Which
term refers to the localization of an antibody-antigen reaction in tissues?
a. Precipitation
b. Agglutination
c. Affinity
d. Immunostaining
6. What
is the purpose of a negative control in immunohistochemistry?
a. Enhance
the signal
b. Validate
the staining protocol
c. Amplify
the antibody-antigen reaction
d. Introduce
variability
7.
Immunological Tests:
8. The
indirect Coombs test is used to detect:
a. ABO
blood group
b. Antibodies
against red blood cells
c. HIV
infection
d. Autoimmune
diseases
9. Which
immunoglobulin is the most abundant in human serum?
a. IgA
b. IgD
c. IgE
d. IgG
10. The
Mantoux test is used for the diagnosis of:
a. Tuberculosis
b. HIV/AIDS
c. Hepatitis
B
d. Malaria
11. What
is the primary purpose of the ELISA test?
a. Assess
liver function
b. Detect
antibodies or antigens
c. Measure
blood glucose levels
d. Evaluate
renal function
12. Which
autoimmune disease is commonly associated with antinuclear antibodies (ANA)?
a. Rheumatoid
arthritis
b. Systemic
lupus erythematosus (SLE)
c. Multiple
sclerosis
d. Psoriasis
13. The
VDRL test is used for the diagnosis of:
a. Syphilis
b. HIV/AIDS
c. Hepatitis
B
d. Gonorrhea
14. Which
immunological test is used to diagnose celiac disease?
a. ANA
test
b. TSH
test
c. Anti-tTG
test
d. PSA
test
15. The
direct Coombs test is used to diagnose:
a. Hemophilia
b. Hemolytic
anemia
c. Leukemia
d. Thalassemia
16. Which
condition is characterized by elevated levels of IgE?
a. Allergic
rhinitis
b. Rheumatoid
arthritis
c. Multiple
myeloma
d. Graves'
disease
17. The
rapid plasma reagin (RPR) test is used for the diagnosis of:
a. HIV/AIDS
b. Syphilis
c. Tuberculosis
d. Hepatitis
C
18. Which
immunoglobulin is involved in allergic reactions and parasitic infections?
a. IgA
b. IgD
c. IgE
d. IgM
19. The
C-reactive protein (CRP) test is a marker for:
a. Inflammation
b. Liver
function
c. Kidney
function
d. Blood
clotting
20. What
is the purpose of the Western blot test in immunology?
a. Identify
blood type
b. Confirm
HIV infection
c. Measure
insulin levels
d. Assess
thyroid function
21. Which
immunological test is used to diagnose infectious mononucleosis?
a. Widal
test
b. Monospot
test
c. Rapid
strep test
d. Tuberculin
skin test
22. The
ABO blood group system is based on the presence of:
a. Antibodies
b. Antigens
on red blood cells
c. White
blood cells
d. Platelets
23. Which
autoimmune disease is characterized by the presence of anti-cyclic
citrullinated peptide (anti-CCP) antibodies?
a. Sjögren's
syndrome
b. Rheumatoid
arthritis
c. Hashimoto's
thyroiditis
d. Graves'
disease
24. The
QuantiFERON-TB Gold test is used for the diagnosis of:
a. Tuberculosis
b. Hepatitis
B
c. HIV/AIDS
d. Malaria
25. What
is the purpose of the rapid strep test?
a. Diagnose
streptococcal infections
b. Assess
liver function
c. Confirm
HIV infection
d. Detect
antibodies against red blood cells
26. Which
immunoglobulin is the first to appear during an immune response?
a. IgA
b. IgM
c. IgE
d. IgG
27. The
anti-dsDNA antibody test is used for the diagnosis of:
a. Rheumatoid
arthritis
b. Systemic
lupus erythematosus (SLE)
c. Multiple
sclerosis
d. Celiac
disease
28. The
Mumps skin test is a type of:
a. Intradermal
test
b. Patch
test
c. Mantoux
test
d. ELISA
test
29. Which
immunoglobulin is involved in mucosal immunity and is found in tears and
saliva?
a. IgA
b. IgD
c. IgE
d. IgG
30. The
erythrocyte sedimentation rate (ESR) is a marker for:
a. Blood
clotting
b. Inflammation
c. Liver
function
d. Renal
function
31. The
RAST test is used to detect:
a. Autoantibodies
b. Allergen-specific
IgE
c. Viral
infections
d. Bacterial
infections
32. The
direct agglutination test is commonly used for the diagnosis of:
a. Dengue
fever
b. Typhoid
fever
c. Malaria
d. Tuberculosis
33. Which
immunological test is used to assess thyroid function?
a. TSH
test
b. ANA
test
c. C-reactive
protein test
d. Rheumatoid
factor test
34. The
hCG test is used for the detection of:
a. Pregnancy
b. Thyroid
disorders
c. Diabetes
d. Multiple
myeloma
35. Which
condition is associated with the presence of anti-glomerular basement membrane
(anti-GBM) antibodies?
a. Goodpasture
syndrome
b. Crohn's
disease
c. Hashimoto's
thyroiditis
d. Myasthenia
gravis
36. The
APTT test is used to assess the function of:
a. Platelets
b. Coagulation
factors
c. Fibrinolysis
d. Vascular
endothelium
37. The
anti-Jo-1 antibody test is associated with which autoimmune disease?
a. Sjögren's
syndrome
b. Dermatomyositis
c. Systemic
lupus erythematosus (SLE)
d. Rheumatoid
arthritis
38. The
thyroglobulin antibody test is used in the diagnosis and monitoring of:
a. Hypothyroidism
b. Hyperthyroidism
c. Diabetes
d. Celiac
disease
39. Which
immunological test is used to diagnose Helicobacter pylori infection?
a. RAST
test
b. Mantoux
test
c. Urea
breath test
d. Monospot
test
40. The
anti-Sm antibody test is associated with which autoimmune disease?
a. Multiple
sclerosis
b. Sjögren's
syndrome
c. Systemic
lupus erythematosus (SLE)
d. Hashimoto's
thyroiditis
41. The
TSH receptor antibody test is used in the diagnosis of:
a. Hypothyroidism
b. Hyperthyroidism
c. Diabetes
d. Celiac
disease
42. The
rapid urease test (RUT) is used to diagnose:
a. Tuberculosis
b. Helicobacter
pylori infection
c. HIV/AIDS
d. Hepatitis
C
43. Which
immunological test is used to assess the risk of developing type 1 diabetes?
a. C-peptide
test
b. GAD
antibody test
c. Thyroglobulin
antibody test
d. Rheumatoid
factor test
44. The
B-type natriuretic peptide (BNP) test is used for the diagnosis of:
a. Heart
failure
b. Diabetes
c. Rheumatoid
arthritis
d. Thyroid
disorders
45. The
anti-centromere antibody test is associated with which autoimmune disease?
a. Systemic
lupus erythematosus (SLE)
b. Scleroderma
c. Rheumatoid
arthritis
d. Myasthenia
gravis
46. The
anti-Müllerian hormone (AMH) test is used in the assessment of:
a. Ovarian
function
b. Thyroid
function
c. Renal
function
d. Liver
function
47. Which
immunological test is used to diagnose antiphospholipid syndrome?
a. Lupus
anticoagulant test
b. Anti-dsDNA
antibody test
c. Anti-Jo-1
antibody test
d. ANA
test
48. The
procalcitonin test is used to diagnose:
a. Bacterial
infections
b. Viral
infections
c. Fungal
infections
d. Autoimmune
diseases
49. The
anti-Scl-70 antibody test is associated with which autoimmune disease?
a. Systemic
lupus erythematosus (SLE)
b. Scleroderma
c. Rheumatoid
arthritis
d. Myasthenia
gravis
50. The
anti-citrullinated protein antibody (ACPA) test is used for the diagnosis of:
a. Rheumatoid
arthritis
b. Multiple
sclerosis
c. Systemic
lupus erythematosus (SLE)
d. Crohn's
disease
51. The
D-dimer test is used in the diagnosis of:
a. Thrombocytopenia
b. Disseminated
intravascular coagulation (DIC)
c. Hemophilia
d. von
Willebrand disease
Question |
Answer |
Question |
Answer |
Question |
Answer |
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Answer |
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Answer |
1 |
b |
11 |
b |
21 |
b |
31 |
b |
41 |
a |
2 |
b |
12 |
a |
22 |
b |
32 |
a |
42 |
c |
3 |
b |
13 |
c |
23 |
a |
33 |
a |
43 |
c |
4 |
b |
14 |
b |
24 |
a |
34 |
c |
44 |
b |
5 |
d |
15 |
c |
25 |
b |
35 |
a |
45 |
a |
6 |
b |
16 |
b |
26 |
b |
36 |
b |
46 |
a |
7 |
b |
17 |
b |
27 |
a |
37 |
a |
47 |
a |
8 |
d |
18 |
a |
28 |
a |
38 |
c |
48 |
b |
9 |
a |
19 |
c |
29 |
b |
39 |
c |
49 |
a |
10 |
b |
20 |
b |
30 |
b |
40 |
b |
50 |
b |