MCQ Immunology

 

 

1.       What is the primary purpose of immunohistochemistry in pathology?

a.       Stain nuclei

b.       Visualize antigens in tissues

c.       Demonstrate blood vessels

d.       Assess cell morphology

 

2.       Which enzyme is commonly used in immunohistochemistry as a chromogen?

a.       Alkaline phosphatase

b.       Horseradish peroxidase

c.       β-Galactosidase

d.       Glucose oxidase

 

3.       CD3 staining is used to identify:

a.       B cells

b.       T cells

c.       Macrophages

d.       Natural killer cells

 

4.       What is the primary function of a secondary antibody in immunohistochemistry?

a.       Bind to antigens on tissues

b.       Amplify the signal

c.       Tag cells for phagocytosis

d.       Enhance tissue fixation

 

5.       Which term refers to the localization of an antibody-antigen reaction in tissues?

a.       Precipitation

b.       Agglutination

c.       Affinity

d.       Immunostaining

 

6.       What is the purpose of a negative control in immunohistochemistry?

a.       Enhance the signal

b.       Validate the staining protocol

c.       Amplify the antibody-antigen reaction

d.       Introduce variability

 

7.       Immunological Tests:

 

8.       The indirect Coombs test is used to detect:

a.       ABO blood group

b.       Antibodies against red blood cells

c.       HIV infection

d.       Autoimmune diseases

 

9.       Which immunoglobulin is the most abundant in human serum?

a.       IgA

b.       IgD

c.       IgE

d.       IgG

 

10.   The Mantoux test is used for the diagnosis of:

a.       Tuberculosis

b.       HIV/AIDS

c.       Hepatitis B

d.       Malaria

 

11.   What is the primary purpose of the ELISA test?

a.       Assess liver function

b.       Detect antibodies or antigens

c.       Measure blood glucose levels

d.       Evaluate renal function

 

12.   Which autoimmune disease is commonly associated with antinuclear antibodies (ANA)?

a.       Rheumatoid arthritis

b.       Systemic lupus erythematosus (SLE)

c.       Multiple sclerosis

d.       Psoriasis

 

13.   The VDRL test is used for the diagnosis of:

a.       Syphilis

b.       HIV/AIDS

c.       Hepatitis B

d.       Gonorrhea

 

14.   Which immunological test is used to diagnose celiac disease?

a.       ANA test

b.       TSH test

c.       Anti-tTG test

d.       PSA test

 

15.   The direct Coombs test is used to diagnose:

a.       Hemophilia

b.       Hemolytic anemia

c.       Leukemia

d.       Thalassemia

 

16.   Which condition is characterized by elevated levels of IgE?

a.       Allergic rhinitis

b.       Rheumatoid arthritis

c.       Multiple myeloma

d.       Graves' disease

 

17.   The rapid plasma reagin (RPR) test is used for the diagnosis of:

a.       HIV/AIDS

b.       Syphilis

c.       Tuberculosis

d.       Hepatitis C

 

18.   Which immunoglobulin is involved in allergic reactions and parasitic infections?

a.       IgA

b.       IgD

c.       IgE

d.       IgM

 

19.   The C-reactive protein (CRP) test is a marker for:

a.       Inflammation

b.       Liver function

c.       Kidney function

d.       Blood clotting

 

20.   What is the purpose of the Western blot test in immunology?

a.       Identify blood type

b.       Confirm HIV infection

c.       Measure insulin levels

d.       Assess thyroid function

 

21.   Which immunological test is used to diagnose infectious mononucleosis?

a.       Widal test

b.       Monospot test

c.       Rapid strep test

d.       Tuberculin skin test

 

22.   The ABO blood group system is based on the presence of:

a.       Antibodies

b.       Antigens on red blood cells

c.       White blood cells

d.       Platelets

 

23.   Which autoimmune disease is characterized by the presence of anti-cyclic citrullinated peptide (anti-CCP) antibodies?

a.       Sjögren's syndrome

b.       Rheumatoid arthritis

c.       Hashimoto's thyroiditis

d.       Graves' disease

 

24.   The QuantiFERON-TB Gold test is used for the diagnosis of:

a.       Tuberculosis

b.       Hepatitis B

c.       HIV/AIDS

d.       Malaria

 

25.   What is the purpose of the rapid strep test?

a.       Diagnose streptococcal infections

b.       Assess liver function

c.       Confirm HIV infection

d.       Detect antibodies against red blood cells

 

26.   Which immunoglobulin is the first to appear during an immune response?

a.       IgA

b.       IgM

c.       IgE

d.       IgG

 

27.   The anti-dsDNA antibody test is used for the diagnosis of:

a.       Rheumatoid arthritis

b.       Systemic lupus erythematosus (SLE)

c.       Multiple sclerosis

d.       Celiac disease

 

28.   The Mumps skin test is a type of:

a.       Intradermal test

b.       Patch test

c.       Mantoux test

d.       ELISA test

 

29.   Which immunoglobulin is involved in mucosal immunity and is found in tears and saliva?

a.       IgA

b.       IgD

c.       IgE

d.       IgG

 

30.   The erythrocyte sedimentation rate (ESR) is a marker for:

a.       Blood clotting

b.       Inflammation

c.       Liver function

d.       Renal function

 

31.   The RAST test is used to detect:

a.       Autoantibodies

b.       Allergen-specific IgE

c.       Viral infections

d.       Bacterial infections

 

32.   The direct agglutination test is commonly used for the diagnosis of:

a.       Dengue fever

b.       Typhoid fever

c.       Malaria

d.       Tuberculosis

 

33.   Which immunological test is used to assess thyroid function?

a.       TSH test

b.       ANA test

c.       C-reactive protein test

d.       Rheumatoid factor test

 

34.   The hCG test is used for the detection of:

a.       Pregnancy

b.       Thyroid disorders

c.       Diabetes

d.       Multiple myeloma

 

35.   Which condition is associated with the presence of anti-glomerular basement membrane (anti-GBM) antibodies?

a.       Goodpasture syndrome

b.       Crohn's disease

c.       Hashimoto's thyroiditis

d.       Myasthenia gravis

 

36.   The APTT test is used to assess the function of:

a.       Platelets

b.       Coagulation factors

c.       Fibrinolysis

d.       Vascular endothelium

 

37.   The anti-Jo-1 antibody test is associated with which autoimmune disease?

a.       Sjögren's syndrome

b.       Dermatomyositis

c.       Systemic lupus erythematosus (SLE)

d.       Rheumatoid arthritis

 

38.   The thyroglobulin antibody test is used in the diagnosis and monitoring of:

a.       Hypothyroidism

b.       Hyperthyroidism

c.       Diabetes

d.       Celiac disease

 

39.   Which immunological test is used to diagnose Helicobacter pylori infection?

a.       RAST test

b.       Mantoux test

c.       Urea breath test

d.       Monospot test

 

40.   The anti-Sm antibody test is associated with which autoimmune disease?

a.       Multiple sclerosis

b.       Sjögren's syndrome

c.       Systemic lupus erythematosus (SLE)

d.       Hashimoto's thyroiditis

 

41.   The TSH receptor antibody test is used in the diagnosis of:

a.       Hypothyroidism

b.       Hyperthyroidism

c.       Diabetes

d.       Celiac disease

 

42.   The rapid urease test (RUT) is used to diagnose:

a.       Tuberculosis

b.       Helicobacter pylori infection

c.       HIV/AIDS

d.       Hepatitis C

 

43.   Which immunological test is used to assess the risk of developing type 1 diabetes?

a.       C-peptide test

b.       GAD antibody test

c.       Thyroglobulin antibody test

d.       Rheumatoid factor test

 

44.   The B-type natriuretic peptide (BNP) test is used for the diagnosis of:

a.       Heart failure

b.       Diabetes

c.       Rheumatoid arthritis

d.       Thyroid disorders

 

45.   The anti-centromere antibody test is associated with which autoimmune disease?

a.       Systemic lupus erythematosus (SLE)

b.       Scleroderma

c.       Rheumatoid arthritis

d.       Myasthenia gravis

 

46.   The anti-Müllerian hormone (AMH) test is used in the assessment of:

a.       Ovarian function

b.       Thyroid function

c.       Renal function

d.       Liver function

 

47.   Which immunological test is used to diagnose antiphospholipid syndrome?

a.       Lupus anticoagulant test

b.       Anti-dsDNA antibody test

c.       Anti-Jo-1 antibody test

d.       ANA test

 

48.   The procalcitonin test is used to diagnose:

a.       Bacterial infections

b.       Viral infections

c.       Fungal infections

d.       Autoimmune diseases

 

49.   The anti-Scl-70 antibody test is associated with which autoimmune disease?

a.       Systemic lupus erythematosus (SLE)

b.       Scleroderma

c.       Rheumatoid arthritis

d.       Myasthenia gravis

 

50.   The anti-citrullinated protein antibody (ACPA) test is used for the diagnosis of:

a.       Rheumatoid arthritis

b.       Multiple sclerosis

c.       Systemic lupus erythematosus (SLE)

d.       Crohn's disease

 

51.   The D-dimer test is used in the diagnosis of:

a.       Thrombocytopenia

b.       Disseminated intravascular coagulation (DIC)

c.       Hemophilia

d.       von Willebrand disease

 

 

Question

Answer

Question

Answer

Question

Answer

Question

Answer

Question

Answer

1

b

11

b

21

b

31

b

41

a

2

b

12

a

22

b

32

a

42

c

3

b

13

c

23

a

33

a

43

c

4

b

14

b

24

a

34

c

44

b

5

d

15

c

25

b

35

a

45

a

6

b

16

b

26

b

36

b

46

a

7

b

17

b

27

a

37

a

47

a

8

d

18

a

28

a

38

c

48

b

9

a

19

c

29

b

39

c

49

a

10

b

20

b

30

b

40

b

50

b

 

Previous Post Next Post