1. What
is the primary function of platelets in hemostasis?
a. Oxygen
transport
b. Clot
formation
c. Immune
response
d. pH
regulation
2. Which
platelet aggregation pathway is initiated by ADP?
a. Intrinsic
pathway
b. Extrinsic
pathway
c. Common
pathway
d. Secondary
pathway
3. What
is the role of tissue factor in the extrinsic pathway of coagulation?
a. Activates
platelets
b. Initiates
clot formation
c. Inhibits
fibrinolysis
d. Enhances
platelet aggregation
4. Which
vitamin is essential for the synthesis of clotting factors II, VII, IX, and X?
a. Vitamin
A
b. Vitamin
C
c. Vitamin
D
d. Vitamin
K
5. What
does the activated partial thromboplastin time (APTT) assess?
a. Intrinsic
pathway
b. Extrinsic
pathway
c. Platelet
function
d. Fibrinolysis
6. Which
of the following is a platelet adhesion molecule?
a. Fibrinogen
b. Thrombin
c. Factor
VIII
d. von
Willebrand factor
7. Sudan
Black B is used to stain cells for the detection of:
a. Lymphomas
b. Myeloid
leukemia
c. Hodgkin's
disease
d. Multiple
myeloma
8. The
presence of Auer rods is characteristic of:
a. Chronic
lymphocytic leukemia
b. Acute
myeloid leukemia
c. Hodgkin's
lymphoma
d. Multiple
myeloma
9. Which
cytochemical stain is commonly used to detect iron in bone marrow aspirates?
a. Prussian
blue
b. Wright's
stain
c. Giemsa
stain
d. Toluidine
blue
10. In
hemostasis, what is the final step in the formation of a stable blood clot?
a. Fibrinolysis
b. Platelet
aggregation
c. Clot
retraction
d. Coagulation
cascade
11. Which
of the following factors is NOT involved in the intrinsic pathway of
coagulation?
a. Factor
VIII
b. Factor
IX
c. Factor
VII
d. Factor
XII
12. What
is the purpose of the prothrombin time (PT) test?
a. Assess
platelet function
b. Evaluate
the intrinsic pathway
c. Monitor
anticoagulant therapy
d. Measure
fibrinolysis activity
13. Which
clotting factor deficiency is associated with hemophilia A?
a. Factor
II
b. Factor
V
c. Factor
VIII
d. Factor
X
14. The
Philadelphia chromosome is a characteristic cytogenetic abnormality in which
hematological malignancy?
a. Chronic
lymphocytic leukemia
b. Acute
lymphoblastic leukemia
c. Chronic
myeloid leukemia
d. Multiple
myeloma
15. Which
of the following is a characteristic feature of lymphoma cells on cytochemical
staining?
a. Auer
rods
b. Reed-Sternberg
cells
c. Smudge
cells
d. Blasts
16. The
bleeding time test primarily assesses the function of:
a. Platelets
b. Coagulation
factors
c. Fibrinolysis
d. Vascular
endothelium
17. Which
vitamin deficiency can lead to impaired platelet function?
a. Vitamin
A
b. Vitamin
B12
c. Vitamin
C
d. Vitamin
D
18. What
is the primary function of von Willebrand factor in hemostasis?
a. Platelet
activation
b. Coagulation
cascade initiation
c. Clot
retraction
d. Platelet
adhesion
19. The
presence of Bence Jones proteins in urine is associated with which
hematological malignancy?
a. Hodgkin's
lymphoma
b. Multiple
myeloma
c. Acute
lymphoblastic leukemia
d. Chronic
myeloid leukemia
20. Which
coagulation factor is activated by thrombin in the final common pathway of
coagulation?
a. Factor
V
b. Factor
IX
c. Factor
XIII
d. Factor
VII
21. What
is the primary function of the spleen in hematopoiesis?
a. Red
blood cell destruction
b. Platelet
production
c. White
blood cell maturation
d. Hemoglobin
synthesis
22. Which
cytochemical stain is used to demonstrate reticulin fibers in bone marrow
biopsies?
a. Prussian
blue
b. Wright's
stain
c. Silver
stain
d. Giemsa
stain
23. What
is the significance of the D-dimer test in hemostasis assessment?
a. Detection
of clotting factor deficiencies
b. Monitoring
anticoagulant therapy
c. Diagnosis
of disseminated intravascular coagulation (DIC)
d. Assessment
of platelet function
24. The
clot retraction process is primarily mediated by which cellular component?
a. Platelets
b. Red
blood cells
c. Neutrophils
d. Lymphocytes
25. In
which phase of hemostasis does fibrinolysis occur?
a. Clot
formation
b. Clot
retraction
c. Clot
stabilization
d. Clot
dissolution
26. Which
of the following conditions is associated with prolonged bleeding time?
a. Thrombocytosis
b. Hemophilia
c. Thrombocytopenia
d. Vitamin
K deficiency
27. The
Ristocetin-induced platelet aggregation test assesses the function of which
clotting factor?
a. Factor
I (Fibrinogen)
b. Factor
V
c. Factor
VIII
d. Factor
XIII
28. What
is the primary function of the endothelium in hemostasis?
a. Platelet
aggregation
b. Clot
initiation
c. Anticoagulation
d. Fibrinolysis
29. Which
of the following is a characteristic feature of chronic myeloid leukemia (CML)
on peripheral blood smear?
a. Smudge
cells
b. Philadelphia
chromosome
c. Auer
rods
d. Reed-Sternberg
cells
30. Which
coagulation factor deficiency is associated with hemophilia B?
a. Factor
II
b. Factor
VII
c. Factor
IX
d. Factor
X
31. The
presence of Howell-Jolly bodies in peripheral blood smears is indicative of
dysfunction in which organ?
a. Liver
b. Spleen
c. Kidney
d. Bone
marrow
32. Which
laboratory test is used to monitor the therapeutic effect of heparin?
a. Prothrombin
time (PT)
b. Activated
partial thromboplastin time (APTT)
c. International
normalized ratio (INR)
d. Thrombin
time
33. The
JAK2 mutation is commonly associated with which myeloproliferative disorder?
a. Essential
thrombocythemia
b. Polycythemia
vera
c. Myelofibrosis
d. Chronic
lymphocytic leukemia
34. What
is the primary function of factor XIII in the coagulation cascade?
a. Platelet
activation
b. Clot
initiation
c. Clot
stabilization
d. Fibrinolysis
35. The
presence of Rouleaux formation in peripheral blood smears is associated with
which condition?
a. Iron
deficiency anemia
b. Multiple
myeloma
c. Hemophilia
d. Thrombocytopenia
36. Which
of the following conditions is characterized by a prolonged thrombin time?
a. Hemophilia
b. Disseminated
intravascular coagulation (DIC)
c. von
Willebrand disease
d. Factor
XIII deficiency
37. The
Bernard-Soulier syndrome is characterized by a deficiency in which platelet
receptor?
a. GPIb-IX
b. GPVI
c. Integrin
alphaIIb-beta3
d. P-selectin
38. What
is the primary function of plasmin in the fibrinolytic system?
a. Clot
initiation
b. Clot
stabilization
c. Clot
retraction
d. Clot
dissolution
39. Which
of the following cytochemical stains is commonly used to identify lymphocytes
in peripheral blood smears?
a. Sudan
Black B
b. Wright's
stain
c. Prussian
blue
d. Toluidine
blue
40. The
presence of Heinz bodies in red blood cells is associated with the ingestion of
which substance?
a. Lead
b. Iron
c. G6PD
deficiency
d. Folate
41. What
is the primary function of antithrombin in the coagulation cascade?
a. Clot
initiation
b. Clot
stabilization
c. Clot
retraction
d. Inhibition
of clotting factors
42. Which
of the following conditions is characterized by a deficiency of factor XI?
a. Hemophilia
A
b. Hemophilia
B
c. Hemophilia
C
d. von
Willebrand disease
43. The
Tartrate-Resistant Acid Phosphatase (TRAP) stain is used to identify cells
associated with which hematological malignancy?
a. Acute
myeloid leukemia
b. Chronic
lymphocytic leukemia
c. Multiple
myeloma
d. Hodgkin's
lymphoma
44. Which
coagulation factor is activated by the intrinsic pathway and plays a role in
the common pathway of coagulation?
a. Factor
II (Prothrombin)
b. Factor
VIII
c. Factor
X
d. Factor
XIII
45. The
presence of blasts in the peripheral blood is characteristic of which
hematological malignancy?
a. Chronic
myeloid leukemia (CML)
b. Acute
myeloid leukemia (AML)
c. Chronic
lymphocytic leukemia (CLL)
d. Hodgkin's
lymphoma
46. Which
of the following is a characteristic feature of disseminated intravascular
coagulation (DIC)?
a. Prolonged
APTT
b. Thrombocytosis
c. Elevated
fibrinogen levels
d. Increased
antithrombin levels
47. Which
clotting factor is vitamin K-dependent and is essential for the amplification
of the coagulation cascade?
a. Factor
II (Prothrombin)
b. Factor
VII
c. Factor
IX
d. Factor
XIII
48. The
presence of schistocytes on peripheral blood smear is indicative of:
a. Hemophilia
b. Thrombotic
thrombocytopenic purpura (TTP)
c. von
Willebrand disease
d. Essential
thrombocythemia
49. Which
of the following conditions is associated with a deficiency of intrinsic
factor?
a. Hemophilia
A
b. von
Willebrand disease
c. Thrombotic
thrombocytopenic purpura (TTP)
d. Pernicious
anemia
50. The
BCR-ABL fusion gene is associated with which hematological malignancy?
a. Chronic
myeloid leukemia (CML)
b. Acute
lymphoblastic leukemia (ALL)
c. Multiple
myeloma
d. Non-Hodgkin's
lymphoma
|
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1 |
b |
11 |
c |
21 |
a |
31 |
b |
41 |
d |
|
2 |
a |
12 |
c |
22 |
c |
32 |
b |
42 |
c |
|
3 |
b |
13 |
c |
23 |
c |
33 |
c |
43 |
c |
|
4 |
d |
14 |
c |
24 |
a |
34 |
c |
44 |
c |
|
5 |
a |
15 |
c |
25 |
d |
35 |
b |
45 |
b |
|
6 |
d |
16 |
a |
26 |
c |
36 |
b |
46 |
a |
|
7 |
b |
17 |
c |
27 |
c |
37 |
a |
47 |
a |
|
8 |
b |
18 |
d |
28 |
c |
38 |
d |
48 |
b |
|
9 |
a |
19 |
b |
29 |
b |
39 |
b |
49 |
b |
|
10 |
c |
20 |
d |
30 |
c |
40 |
c |
50 |
a |